The series tells the story of five teenage girls who are chosen to be the new Guardians of Kandrakar, protectors of the center of the universe from people and creatures who wish to cause harm to it. For this purpose, powers over the five elements have been given to them. The new guardians are Will, Irma, Taranee, Cornelia and Hay Lin, whose initials form the title acronym "W.I.T.C.H.".