Edit: after viewing a lot of comments saying it's because he lost his 5 year old son, it's actually his 4 YEAR OLD son, just to clear that up
"Then, on 20 March 1991, Conor, who was four years of age, died when he fell from the 53rd-story window of his mother's friend's New York City apartment, landing on the roof of an adjacent four-story building. Clapton's grief was expressed in the song "Tears in Heaven","
~Peach
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